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From the first quarter of 2019, Guayaquil will be the new destination of JetBlue in Ecuador, which will operate with 1 daily flight from Fort Lauderdale.
The sale of JetBlue tickets between Fort Lauderdale and Guayaquil: www.nlarenas.com/2018/10/ya-se-venden-los-boletos-fort-lauderdale-guayaquil-de-jetblue/.
UPDATE 12/04/2018
With date 28 November 2018, JetBlue was authorized to operate the Fort Lauderdale route – Guayaquil with up 7 weekly flights with third and fourth freedoms of the air traffic rights:

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JetBlue will launch a new destination in Ecuador at José Joaquín de Olmedo International Airport with flights from Fort Lauderdale-Hollywood International Airport.
The service will operate with one daily flight and is expected to take off in the first quarter of 2019. Guayaquil becomes JetBlue's second city in Ecuador and joins Quito launched in 2016 and will be JetBlue's sixth city in South America.
Cost
Tickets will go on sale in the coming weeks on the airline's website, according to a press release..
Initial and promotional values have not yet been made public, but they would border the $350 dollars with taxes included round trip, this taking into account the current costs of the competition on this route.
Itinerary
The new service between USA and Ecuador will be operated on Airbus A320 aircraft offering the airline's award-winning service with comfortable seats; complementary and unlimited snacks; free new release hollywood movies; and the largest legroom in the segment.
The schedule will be announced in the coming weeks., once the sale of this destination starts.
Competition towards Florida
It should be noted, so, JetBlue to become third airline operating between Main Port and Fort Lauderdale, joining Spirit Airlines with 1 daily flight and Tame EP with 4 weekly flights.
To these flights too, you have to add the 2 daily flights that American Airlines has direct access to Miami International Airport from Guayaquil.
With 4 operators flying to Florida, they will be 32 weekly flights from Guayaquil, which shows the importance of this market and is the main connection city to that state and to the United States from Ecuador in general..
Without exact flight start date and still without starting the new route process before the aeronautical authority of Ecuador, Guayaquil Airport adds a new airline, that will allow you to continue growing, all pointing towards the construction of Daular.
We will continue to update as new information becomes known..
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excellent option. Guayaquileños have more places for the northern country, I hope other routes open in the same country, maybe New Jersey or Los Angeles. It would be good if Lan or Air Europa gave us a flight a week to Barcelona.
Barcelona is a pending destination between Europe and Ecuador, I would think that in the future it will come, maybe with LEVEL.